StimCell's eBalance(R) Technology Demonstrates Significant Enhancement of Mitochondrial Function in Neuronal Study

VANCOUVER, BC, November 12, 2026 (Newswire.com) - StimCell Energetics Inc. (OTCQB:STME) ("StimCell" or the "Company"), a biotech pioneer targeting cellular energy to enhance wellness, anti-aging, and longevity, today announced positive preliminary results from its research collaboration with the St. Boniface Hospital Albrechtsen Research Centre (affiliated with the University of Manitoba) and Principal Investigator Professor Paul Fernyhough.

The study, conducted under the service agreement announced in December 2025, evaluated the effects of StimCell's proprietary eBalance^® microcurrent technology on mitochondrial function in cultured healthy adult rat sensory neurons. Using established Seahorse-based bioenergetic assays in Dr. Fernyhough's laboratory, the research measured oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) to assess key parameters of cellular energy production.

Initial results demonstrate that eBalance^® stimulation produces statistically significant improvements in mitochondrial respiratory function compared with unstimulated controls (mean ± SEM, n=5; one-way ANOVA with Dunnett's post hoc test):

• Basal respiration was significantly elevated by 49% (p 0.005)
• Maximal respiration increased by 119% (p 0.0001)
• Spare respiratory capacity was substantially enhanced by 174% (p 0.0005)
• ECAR at peak stimulation was also significantly higher by approximately 85-90% (p 0.0001), indicating elevated glycolytic activity

These findings indicate that eBalance^® stimulation increases both the baseline energy output of sensory neurons and their capacity to respond to increased energy demand. Spare respiratory capacity, in particular, reflects the ability of mitochondria to meet sudden or sustained energy requirements, a parameter frequently impaired in conditions associated with mitochondrial dysfunction.

"These preliminary data are very promising and demonstrate a clear, statistically significant effect of eBalance^® stimulation on multiple parameters of mitochondrial function in healthy adult rat sensory neurons," said Professor Paul Fernyhough. "Sensory neurons derived from adult rat dorsal root ganglia are a well-established experimental model that closely parallels human sensory neurons in their morphology and physiology. Given the central role of mitochondrial bioenergetics in neuronal health and the pathogenesis of diabetic neuropathy, further investigation of these findings is warranted and underway."

Mitochondrial impairment is a well-documented feature of aging, diabetic neuropathy, and other neurodegenerative processes. Enhancing mitochondrial bioenergetics in sensory neurons is therefore of particular scientific and potential clinical interest. The magnitude of the improvements observed in this preliminary work is consistent with beneficial bioenergetic shifts previously reported in the literature with established interventions such as insulin and neurotrophic factors in similar neuronal models.

"We are very pleased with these early results from Dr. Fernyhough's laboratory," said David Jeffs, CEO of StimCell Energetics. "The ability of our eBalance^® technology to produce measurable, statistically significant improvements in mitochondrial performance in a rigorous academic setting is an important milestone. It strengthens the scientific foundation of our platform and supports our broader goal of developing practical tools that help eBalance^® users support cellular energy, wellness, and healthy aging."

The Company notes that these are preliminary results from initial experimental rounds. Additional analyses, including longer-term stimulation studies and complementary molecular assays, are ongoing and the Company is currently in discussions to extend its research program. A comprehensive report is expected upon completion of the full experimental program.

Forward Looking Statements

This press release contains forward-looking statements. Forward-looking statements are subject to risks, uncertainties and assumptions and are identified by words such as "expects", "intends", "estimates", "projects", "anticipates", "believes", "could", and other similar words. All statements addressing product performance, events, or developments that the Company expects or anticipates will occur in the future are forward-looking statements. Because the statements are forward-looking, they should be evaluated in light of important risk factors and uncertainties, some of which are described in the Company's Quarterly, Annual and Current Reports filed with the United States Securities and Exchange Commission (the "SEC"). Should one or more of these risks or uncertainties materialize, or should any of the Company's underlying assumptions prove incorrect, actual results may vary materially from those currently anticipated. In addition, undue reliance should not be placed on Company's forward-looking statements. Except as required by law, StimCell Energetics Inc. disclaims any obligation to update or publicly announce any revisions to any of the forward-looking statements contained in this press release. There can be no assurance that such statements will prove to be accurate and actual results and future events could differ materially from those anticipated in such statements. No stock exchange, securities commission or other regulatory body has reviewed nor accepts responsibility for the adequacy or accuracy of this release. Investors are advised to carefully review the reports and documents that StimCell Energetics Inc. files from time to time with the SEC, including its Annual, Quarterly and Current Reports.

SOURCE: StimCell Energetics

Source: StimCell Energetics

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